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Table 1 Demographics of subjects

From: Cerebrospinal fluid phosphorylated tau, visinin-like protein-1, and chitinase-3-like protein 1 in mild cognitive impairment and Alzheimer’s disease

Characteristics CN (n = 32) sMCI (n = 24) pMCI (n = 47) AD (n = 18)
Age, years [mean (SE)] 76.0 (1.0) 76.7 (1.1) 73.1 (1.0) 74.3 (1.6)
Gender, male [n (%)] 19 (59.4%) 17 (70.8%)d 33 (70.2%)d 7 (38.9%)
Education, years [mean (SE)] 16.1 (0.6) 16.6(0.5) 15.9 (0.4) 15.2 (0.7)
APOE ε4+ [n (%)] 5 (15.6%)c, d 8 (33.3%)c, d 28 (59.6%)a, b 13 (72.2%)a, b
MMSE at baseline, [mean (SE)] 29.2 (0.2)b, c, d 27.2 (0.3)a, d 26.6 (0.2)a, d 24.2 (0.5)a, b, c
MMSE at 24 m, [mean (SE)] 29.3 (0.2) b, c, d 26.7 (0.5)a, c, d 24.3 (0.5)a, b, d 18.1 (1.6)a, b, c
Follow-up, years, [mean (SE)] 7.0 (0.4)b, c, d 4.7 (0.5)a, d 5.7 (0.4)a, d 2.6 (0.2)a, b, c
  1. P values indicate the values assessed with analyses of variance for each variable except gender and APOE ε4, where a contingency chi-square was performed. Post hoc analysis provided significant differences between groups: afrom CN; bfrom sMCI; cfrom pMCI; dfrom AD
  2. Abbreviations: SE Standard error, APOE apolipoprotein E, MMSE Mini-mental State Examination, CN cognitively normal, sMCI stable mild cognitive impairment, pMCI progressive mild cognitive impairment, AD Alzheimer’s disease