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Fig. 6 | Translational Neurodegeneration

Fig. 6

From: Dopaminergic neurons show increased low-molecular-mass protein 7 activity induced by 6-hydroxydopamine in vitro and in vivo

Fig. 6

β5i regulates antigen presentation on DA neurons under 6-OHDA in vivo. a The expression and collocation of TAP1 after 6-OHDA for 1 day in the rat. b, c The expression of Bip and TAP1 at 24 h after inhibition with PR-957 in the 6-OHDA hemilesioned rats. d TH+ neurons in the SN were collected by LCM. The precaptured (Pre), postcaptured (Post) and captured (Cap) images are shown in the right column, and TH+ cells are indicated with red arrows. Scale bar = 100 μm. e qRT-PCR result of captured TH+ cells (n = 6 experiments). Error bars represent SD. * P < 0.05, compared with control; # P < 0.05, compared with 6-OHDA treatment but without PR-957

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Translational Neurodegeneration

ISSN: 2047-9158

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