Fig. 3
From: Ultra-High Field Diffusion MRI Reveals Early Axonal Pathology in Spinal Cord of ALS mice
Fiber organization tractography anomalies and ultrastructural histological changes in axons from ALS mice. a Representative WM tractography fiber reconstructions from lumbar spinal cord sections showing early changes in microstructural organization. Scale bar =1 mm. b Three-dimensional confocal z-stack reconstructions from spinal cord WM (white square) showing early axonal structural anomalies in the YFP, G93A-SOD1 (ALS) mice. Scale bar =10 μm. Abbreviations: WM, white matter; YFP, yellow fluorescent protein