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Table 4 Cognitive Performance of PD patients with and without treatment

From: Cognitive characteristics in Chinese non-demented PD patients based on gender difference

  Treated PD (n = 31) Untreated PD (n = 29) Controls (n = 100) P-valuea P-valueb P-valuec
Age 57.03 ± 10.19 61.21 ± 8.46 58.2 ± 7.57 0.591 0.061 0.111
Gender(male) 15/31 15/29 38/100 0.402 0.204 1.000
Disease duration 6.16 ± 6.36 2.13 ± 2.79     0.000*
Education 12.70 ± 3.12 13.04 ± 2.85 12.63 ± 3.24 0.765 0.512 0.774
MMSE 29.13 ± 1.12 28.83 ± 1.00 29.03 ± 0.69 0.137 0.350 0.135
Verbal memory
 AVLT-short delayed free recall 5.04 ± 1.99 4.79 ± 1.90 5.29 ± 2.5 0.439 0.264 0.734
 AVLT-long delayed free recall 4.55 ± 1.84 4.38 ± 1.47 4.72 ± 2.72 0.699 0.502 0.994
 AVLT-sum 1 to 5 15.10 ± 5.83 15.96 ± 4.33 26.17 ± 8.15 0.000* 0.000* 0.378
 AVLT-recognition 20.27 ± 3.95 19.78 ± 3.00 20.35 ± 2.89 0.585 0.355 0.788
Non-verbal memory
 Rey-delayed recall 13.86 ± 6.15 17.63 ± 8.67 15.16 ± 6.5 0.347 0.206 0.102
Visuospatial function
 Rey-copy (time) 175.21 ± 58.78 181.75 ± 64.34 165.57 ± 68.41 0.268 0.162 0.854
 Rey-copy (score) 31.62 ± 4.82 34.44 ± 1.58 34.16 ± 1.74 0.006* 0.503 0.016*
 CDT 20.41 ± 7.15 25.04 ± 3.52 25.81 ± 6.3 0.000* 0.252 0.004*
Language
 VFT (animals) 16.17 ± 3.23 16.03 ± 4.01 19.43 ± 19.22 0.358 0.193 0.632
 VFT (cities) 15.10 ± 5.42 12.38 ± 5.00 17.39 ± 5.82 0.021* 0.000* 0.012*
 VFT (alternative) 14.33 ± 4.01 14.59 ± 6.27 17.11 ± 5.02 0.009* 0.003* 0.715
 BNT 23.10 ± 3.41 22.96 ± 3.98 23.63 ± 3.81 0.337 0.323 1.000
Attention/executive function
 SDMT 31.14 ± 13.92 32.62 ± 9.70 43.61 ± 11.6 0.000* 0.000* 0.602
 Stroop (time) 76.17 ± 29.36 79.72 ± 23.15 75.98 ± 24.22 0.699 0.339 0.323
 Stroop (score) 46.79 ± 4.56 46.52 ± 4.73 46.58 ± 7.86 0.027* 0.088 0.827
 TMT-A 75.21 ± 44.69 67.66 ± 18.71 55.77 ± 24.8 0.004* 0.001* 0.873
 TMT-B 163.96 ± 66.04 165.21 ± 53.15 150.55 ± 74.35 0.278 0.063 0.762
  1. Note. MMSE Mini-mental state examination, AVLT Auditory verbal learning test, Rey-delayed recall Delayed recall of Rey-Osterrieth complex figure, Rey-copy Copy of Rey-Osterrieth complex figure, CDT Clock drawing test, VFT Verbal fluency tasks, BNT Boston naming test, SDMT Symbol digit modality test, Stroop Stroop color word interference test, TMT Trail making test
  2. aComparison between Treated PD and Control
  3. bComparison between Untreated PD and Control
  4. cComparison between Treated PD and Untreated PD
  5. *p < 0.05