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Table 4 Cognitive Performance of PD patients with and without treatment

From: Cognitive characteristics in Chinese non-demented PD patients based on gender difference

 

Treated PD (n = 31)

Untreated PD (n = 29)

Controls (n = 100)

P-valuea

P-valueb

P-valuec

Age

57.03 ± 10.19

61.21 ± 8.46

58.2 ± 7.57

0.591

0.061

0.111

Gender(male)

15/31

15/29

38/100

0.402

0.204

1.000

Disease duration

6.16 ± 6.36

2.13 ± 2.79

   

0.000*

Education

12.70 ± 3.12

13.04 ± 2.85

12.63 ± 3.24

0.765

0.512

0.774

MMSE

29.13 ± 1.12

28.83 ± 1.00

29.03 ± 0.69

0.137

0.350

0.135

Verbal memory

 AVLT-short delayed free recall

5.04 ± 1.99

4.79 ± 1.90

5.29 ± 2.5

0.439

0.264

0.734

 AVLT-long delayed free recall

4.55 ± 1.84

4.38 ± 1.47

4.72 ± 2.72

0.699

0.502

0.994

 AVLT-sum 1 to 5

15.10 ± 5.83

15.96 ± 4.33

26.17 ± 8.15

0.000*

0.000*

0.378

 AVLT-recognition

20.27 ± 3.95

19.78 ± 3.00

20.35 ± 2.89

0.585

0.355

0.788

Non-verbal memory

 Rey-delayed recall

13.86 ± 6.15

17.63 ± 8.67

15.16 ± 6.5

0.347

0.206

0.102

Visuospatial function

 Rey-copy (time)

175.21 ± 58.78

181.75 ± 64.34

165.57 ± 68.41

0.268

0.162

0.854

 Rey-copy (score)

31.62 ± 4.82

34.44 ± 1.58

34.16 ± 1.74

0.006*

0.503

0.016*

 CDT

20.41 ± 7.15

25.04 ± 3.52

25.81 ± 6.3

0.000*

0.252

0.004*

Language

 VFT (animals)

16.17 ± 3.23

16.03 ± 4.01

19.43 ± 19.22

0.358

0.193

0.632

 VFT (cities)

15.10 ± 5.42

12.38 ± 5.00

17.39 ± 5.82

0.021*

0.000*

0.012*

 VFT (alternative)

14.33 ± 4.01

14.59 ± 6.27

17.11 ± 5.02

0.009*

0.003*

0.715

 BNT

23.10 ± 3.41

22.96 ± 3.98

23.63 ± 3.81

0.337

0.323

1.000

Attention/executive function

 SDMT

31.14 ± 13.92

32.62 ± 9.70

43.61 ± 11.6

0.000*

0.000*

0.602

 Stroop (time)

76.17 ± 29.36

79.72 ± 23.15

75.98 ± 24.22

0.699

0.339

0.323

 Stroop (score)

46.79 ± 4.56

46.52 ± 4.73

46.58 ± 7.86

0.027*

0.088

0.827

 TMT-A

75.21 ± 44.69

67.66 ± 18.71

55.77 ± 24.8

0.004*

0.001*

0.873

 TMT-B

163.96 ± 66.04

165.21 ± 53.15

150.55 ± 74.35

0.278

0.063

0.762

  1. Note. MMSE Mini-mental state examination, AVLT Auditory verbal learning test, Rey-delayed recall Delayed recall of Rey-Osterrieth complex figure, Rey-copy Copy of Rey-Osterrieth complex figure, CDT Clock drawing test, VFT Verbal fluency tasks, BNT Boston naming test, SDMT Symbol digit modality test, Stroop Stroop color word interference test, TMT Trail making test
  2. aComparison between Treated PD and Control
  3. bComparison between Untreated PD and Control
  4. cComparison between Treated PD and Untreated PD
  5. *p < 0.05