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Table 2 Clusters of regional hypometabolism in aMCI converters relative to aMCI non-converters

From: Cerebral glucose metabolic prediction from amnestic mild cognitive impairment to Alzheimer’s dementia: a meta-analysis

Anatomical label Peak MNI coordinate (x, y, z) Number of voxels SDM-Z value p value
(SDM)
p value (Egger’s test)
Left/Right PCC/precuneus (BAs 23, 7, and 30) −4, −48, 28 1959 −2.73 ~ 0 0.37
Left/Right ACC (BAs 11, 32, 24, and 10) −4, 32, 0 668 −1.72 0.00047 0.23
Left middle temporal gyrus (BAs 21, 20, and 38) −44, 4, − 26 501 −1.66 0.00067 0.16
Left middle temporal gyrus (BAs 21 and 37) −58, −52, −2 185 − 1.65 0.00074 0.13
Left middle frontal gyrus, orbital part (BA 11) −20, 40, −18 22 −1.39 0.0031 0.30
  1. Abbreviations: MCI amnestic mild cognitive impairment, MNI Montreal Neurological Institute, SDM Seed-based d Mapping, PCC posterior cingulate cortex, ACC anterior cingulate cortex, BA Brodmann area