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Table 2 Clinical characteristics of PD patients

From: Clinical features of Parkinson’s disease with and without rapid eye movement sleep behavior disorder

 

pRBD+

pRBD-

p

Hoehn & Yahr stage

2.40 ± 0.90

2.26 ± 0.90

0.299

UPDRS III(total)

26.93 ± 14.62

23.68 ± 15.93

0.174

Bradykinesia (23–26)

8.87 ± 7.05

7.40 ± 6.11

0.292

Freezing, n (%)

8 (26.7)

25 (22.52)

0.750

LcompareA

5.67 ± 4.22

6.17 ± 4.61

0.734

RcompareT

3.01 ± 4.06

1.79 ± 2.08

0.320

PDSS

17.50 ± 9.60

11.70 ± 8.55

<0.001

MMSE

25.30 ± 3.91

26.75 ± 3.97

0.017

HAMA

7.53 ± 5.51

4.53 ± 6.38

0.002

HAMD

10.83 ± 8.60

5.39 ± 7.12

<0.001

Hallucination, n (%)

6 (20.00)

7 (6.30)

0.032

Dementia, n (%)

5(16.67)

13(11.71)

0.538

Anxiety, n (%)

18 (60.00)

25 (22.52)

<0.001

Depression, n (%)

19 (63.33)

27 (24.32)

<0.001

Hyposmia, %

46.67

35.16

0.247

Constipation, %

80.00

57.66

0.033

Orthostatic hypotension, n (%)

7 (23.33)

7 (6.30)

0.012

  1. LcompareA (UPDRS III): UPDRS score in limb compare with axial; RcompareT (UPDRS III): UPDRS score in rigidity compare with tremor; n Number
  2. The pRBD+ PD patients had significantly higher rates of anxiety, depression and visual hallucinations rates. And they had a higher mean PDSS score. Dementia was not significantly difference between two groups. Constipation and OH were more prominent in the pRBD+ group