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Fig. 3 | Translational Neurodegeneration

Fig. 3

From: Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism

Fig. 3

MN degeneration is prevented by QCT infusion, but not by RSV. Representative photomicrographs of Nissl stained ipsilateral and contralateral lumbar ventral spinal cord of rats after 10 days of continuous infusion of: a vehicle or AMPA; b RSV alone or co-infused with AMPA and EX527; c QCT alone or co-infused with AMPA and EX527; d EX527 alone or co-infused with AMPA. Scale bar, 250 μm. e. Quantitative analysis of healthy motor neurons. Number of animals is shown in parentheses. *p < 0.05 versus control, # p < 0.05 versus AMPA, and °p < 0.05 versus QCT 1 nm/d + AMPA. One-way ANOVA followed by Tukey’s post hoc test

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Translational Neurodegeneration

ISSN: 2047-9158

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