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Fig. 2 | Translational Neurodegeneration

Fig. 2

From: Quercetin prevents spinal motor neuron degeneration induced by chronic excitotoxic stimulus by a sirtuin 1-dependent mechanism

Fig. 2

Effects of RSV, QCT and EX527 on motor behavior tasks during chronic AMPA-induced excitotoxicity. a Results of rotarod test and hindlimb grip strength measurement, as indicated, during 10 days of continuous vehicle (control) or AMPA infusions. b RSV effects, alone or co-infused with AMPA and EX527, as indicated. c QCT effects, alone or co-infused with AMPA or EX527. d Effects of EX527 alone or co-infused with AMPA. Number of animals is shown in parentheses. *p < 0.05 and **p < 0.01 versus control, and # p < 0.05 and ## p < 0.01 versus AMPA. Two-way ANOVA followed by Tukey’s post hoc test

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