Specific serum antibody binding to phosphorylated and non-phosphorylated tau in non-cognitively impaired, mildly cognitively impaired, and Alzheimer’s disease subjects: an exploratory study

Table 1 Demographic, clinical, and neuropathologic characteristics for NCI, MCI, and AD subjects

Variables	NCI (n = 10)	MCI (n = 10)	AD (n = 10)
Age, yrs	88.8 ± 4.8 (81.9 – 96.6)	89.8 ± 3.7 (84.3 – 96.4)	88.5 ± 3.0 (83.6 – 92.0)
% Males	40	40	40
Global cognitive functioning score	0.26 ([−0.15] – [1.12])	−0.21 ([−0.54] – [0.26])	−1.31 ([−3.03] – [−1.08])
MMSE score	28.8 ± 1.1 (27 – 30)	26.1 ± 2.2 (23 – 29)	16.9 ± 2.3 (13 – 20)
NFT counts	3.50 ± 2.68 (0.57 – 8.03)	3.81 ± 2.53 (0.80 – 7.18)	8.14 ± 5.87 (2.13 – 17.55)

Summary statistics for age, MMSE scores, and NFT counts are shown as mean ± SD (top line) and range (bottom line), while global cognitive functioning scores are shown as median (top line) and range (bottom line). (NCI No cognitive impairment, MCI Mild cognitive impairment, AD Alzheimer’s disease, MMSE Mini Mental State Examination, NFT Neurofibrillary tangles)

ISSN: 2047-9158