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Table 1 Neuropsychological assessments used for level II criteria (n = 96)

From: Caregiver burden is increased in Parkinson’s disease with mild cognitive impairment (PD-MCI)

Patient groups PD-N(n = 51) PD-MCI(n = 30) PD-D(n = 15) Analysis (F 2,93 )
MoCAa 26.64 ± 2.16 24.53 ± 3.08 21.33 ± 2.32 27.12, p < .0001
Attention, Working Memory and Processing Speed
 DigitsF/B .54 ± 0.93 .14 ± 0.69 −.37 ± 0.64 7.69, p < .01
 Digit Ordering −.60 ± 1.06 −1.33 ± 1.10 −2.16 ± 0.89 13.52, p < .001
 TEA (Map Search) −.46 ± 0.84 −1.40 ± 0.85 −1.91 ± 0.72 23.6, p < .001
 Stroop colour .09 ± 0.80 −.60 ± 1.14 −1.13 ± 1.07 15.03, p < .001
 Stroop word .15 ± 0.73 −.34 ± 1.06 −.68 ± 1.07 6.17, p < .01
 Trails A .32 ± 0.69 −.41 ± 0.99 −1.7 ± 1.22 8.83, p < .001
 Domain Score .01 ± 0.50 −.65 ± 0.51 −1.40 ± 0.52 47.78, p < .001
 Domain Pass/Fail 51/0 13/17 2/13  
Executive Function
 Letter Fluency .61 ± 1.45 .28 ± 1.24 −.42 ± 1.40 3.32, p < .05
 Action Fluency −.78 ± 1.08 −1.45 ± 1.09 −1.76 ± 1.03 6.56, p < .01
 Category Fluency .68 ± 1.14 .07 ± 1.09 −.95 ± 1.17 12.55, p < .001
 Category Switching .27 ± 1.12 −.52 ± 1.27 −1.95 ± .89 22.80, p < .001
 Trails B .28 ± 0.83 −.30 ± 1.13 −2.31 ± 0.84 44.03, p < .0001
 Stroop Interference .31 ± 1.04 −.45 ± 0.78 −1.66 ± 0.70 35.01, p < .0001
 Domain Score .23 ± 0.74 −.40 ± 0.72 −1.05 ± 0.55 36.05, p < .0001
 Domain Pass/Fail 51/0 15/15 2/13  
Learning & Memory
 CVLT Free recall .59 ± 1.13 −.29 ± 0.96 −1.44 ± 0.90 23.26, p < .001
 CVLT Short delay .31 ± 1.32 −.33 ± 1.28 −1.43 ± 0.53 12.17, p < .001
 CVLT Long delay .38 ± 0.90 −.23 ± 0.98 −.76 ± 0.53 11.38, p < .001
 Rey Immediate .59 ± 1.71 −.56 ± 1.08 −1.34 ± 1.03 12.84, p < .001
 Rey Delayed .58 ± 1.77 −.85 ± 1.15 −1.82 ± 1.08 18.13, p < .001
 Domain Score .50 ± 1.06 −.45 ± 0.80 −1.41 ± 0.46 28.50, p < .0001
 Domain Pass/Fail Visuospatial 51/0 24/6 4/11  
 JOL −.15 ± 0.81 −.99 ± 0.81 −.94 ± 0.84 10.55, p < .001
 Fragmented letters .62 ± 0.58 .10 ± 9.99 .20 ± .08 7.9, p < .05
 Rey Copy .02 ± 1.04 −.85 ± 1.27 −1.61 ± 1.11 14.11, p < .01
 Domain Score .44 ± 0.55 −.31 ± 0.63 −.76 ± 0.57 31.94, p < .0001
 Domain Pass/Fail 51/0 26/4 11/4  
Language
 Boston Naming .21 ± 0.86 .05 ± 1.07 −.11 ± 1.21 F 2,64 = .87, p = .42
 ADAS-Cog .01 ± 0.65 −.18 ± 0.78 −1.16 ± 0.59 14.89, p < .001
 DRS-2 .01 ± 0.57 −.18 ± 0.66 −.62 ± 0.88 5.45, p < .01
 Domain Score .06 ± 0.47 −.10 ± 0.46 −.67 ± 0.57 13.64, p < .001
Domain Pass/Fail 51/0 29/1 14/1  
Global neuropsychological z score .29 ± 0.57 −.45 ± 0.41 −1.29 ± 0.41 62.23, p < .001
  1. Values reported as mean ± standard deviation
  2. aMoCA Montreal Cognitive Assessment, with one missed test; Age and education z scores for all tests except MoCA; global performance was expressed by an aggregate z score by first averaging standardized scores within four cognitive domains and then taking the mean of these four values; the language domain scores were not included in this z score due to the distributions of the normative data