Table 1 Neuropsychological assessments used for level II criteria (n = 96)
From: Caregiver burden is increased in Parkinson’s disease with mild cognitive impairment (PD-MCI)
Patient groups | PD-N(n = 51) | PD-MCI(n = 30) | PD-D(n = 15) | Analysis (F 2,93 ) |
|---|---|---|---|---|
MoCAa | 26.64 ± 2.16 | 24.53 ± 3.08 | 21.33 ± 2.32 | 27.12, p < .0001 |
Attention, Working Memory and Processing Speed | ||||
DigitsF/B | .54 ± 0.93 | .14 ± 0.69 | −.37 ± 0.64 | 7.69, p < .01 |
Digit Ordering | −.60 ± 1.06 | −1.33 ± 1.10 | −2.16 ± 0.89 | 13.52, p < .001 |
TEA (Map Search) | −.46 ± 0.84 | −1.40 ± 0.85 | −1.91 ± 0.72 | 23.6, p < .001 |
Stroop colour | .09 ± 0.80 | −.60 ± 1.14 | −1.13 ± 1.07 | 15.03, p < .001 |
Stroop word | .15 ± 0.73 | −.34 ± 1.06 | −.68 ± 1.07 | 6.17, p < .01 |
Trails A | .32 ± 0.69 | −.41 ± 0.99 | −1.7 ± 1.22 | 8.83, p < .001 |
Domain Score | .01 ± 0.50 | −.65 ± 0.51 | −1.40 ± 0.52 | 47.78, p < .001 |
Domain Pass/Fail | 51/0 | 13/17 | 2/13 | |
Executive Function | ||||
Letter Fluency | .61 ± 1.45 | .28 ± 1.24 | −.42 ± 1.40 | 3.32, p < .05 |
Action Fluency | −.78 ± 1.08 | −1.45 ± 1.09 | −1.76 ± 1.03 | 6.56, p < .01 |
Category Fluency | .68 ± 1.14 | .07 ± 1.09 | −.95 ± 1.17 | 12.55, p < .001 |
Category Switching | .27 ± 1.12 | −.52 ± 1.27 | −1.95 ± .89 | 22.80, p < .001 |
Trails B | .28 ± 0.83 | −.30 ± 1.13 | −2.31 ± 0.84 | 44.03, p < .0001 |
Stroop Interference | .31 ± 1.04 | −.45 ± 0.78 | −1.66 ± 0.70 | 35.01, p < .0001 |
Domain Score | .23 ± 0.74 | −.40 ± 0.72 | −1.05 ± 0.55 | 36.05, p < .0001 |
Domain Pass/Fail | 51/0 | 15/15 | 2/13 | |
Learning & Memory | ||||
CVLT Free recall | .59 ± 1.13 | −.29 ± 0.96 | −1.44 ± 0.90 | 23.26, p < .001 |
CVLT Short delay | .31 ± 1.32 | −.33 ± 1.28 | −1.43 ± 0.53 | 12.17, p < .001 |
CVLT Long delay | .38 ± 0.90 | −.23 ± 0.98 | −.76 ± 0.53 | 11.38, p < .001 |
Rey Immediate | .59 ± 1.71 | −.56 ± 1.08 | −1.34 ± 1.03 | 12.84, p < .001 |
Rey Delayed | .58 ± 1.77 | −.85 ± 1.15 | −1.82 ± 1.08 | 18.13, p < .001 |
Domain Score | .50 ± 1.06 | −.45 ± 0.80 | −1.41 ± 0.46 | 28.50, p < .0001 |
Domain Pass/Fail Visuospatial | 51/0 | 24/6 | 4/11 | |
JOL | −.15 ± 0.81 | −.99 ± 0.81 | −.94 ± 0.84 | 10.55, p < .001 |
Fragmented letters | .62 ± 0.58 | .10 ± 9.99 | .20 ± .08 | 7.9, p < .05 |
Rey Copy | .02 ± 1.04 | −.85 ± 1.27 | −1.61 ± 1.11 | 14.11, p < .01 |
Domain Score | .44 ± 0.55 | −.31 ± 0.63 | −.76 ± 0.57 | 31.94, p < .0001 |
Domain Pass/Fail | 51/0 | 26/4 | 11/4 | |
Language | ||||
Boston Naming | .21 ± 0.86 | .05 ± 1.07 | −.11 ± 1.21 | F 2,64 = .87, p = .42 |
ADAS-Cog | .01 ± 0.65 | −.18 ± 0.78 | −1.16 ± 0.59 | 14.89, p < .001 |
DRS-2 | .01 ± 0.57 | −.18 ± 0.66 | −.62 ± 0.88 | 5.45, p < .01 |
Domain Score | .06 ± 0.47 | −.10 ± 0.46 | −.67 ± 0.57 | 13.64, p < .001 |
Domain Pass/Fail | 51/0 | 29/1 | 14/1 | |
Global neuropsychological z score | .29 ± 0.57 | −.45 ± 0.41 | −1.29 ± 0.41 | 62.23, p < .001 |