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Table 1 Linage disequilibrium (LD) of the combined studied SNPs in PD patients and healthy controls

From: Roles of functional catechol-O-methyltransferase genotypes in Chinese patients with Parkinson’s disease

 

Control group

PD group

rs4633

rs4818

rs4680

rs4633

rs4818

rs4680

rs6269

D’

0.90

0.94

0.77

0.91

0.98

1.00

LOD

8.05

48.14

4.84

4.43

48.84

5.49

r 2

0.18

0.85

0.12

0.14

0.92

0.16

rs4633

D’

-

1.00

0.95

-

0.91

1.00

LOD

-

10.20

41.80

-

3.85

49.53

r 2

-

0.21

0.83

-

0.13

0.96

rs4818

D’

-

-

0.94

-

-

1.00

LOD

-

-

7.47

-

-

4.88

r 2

-

-

0.17

-

-

0.16

  1. The LD pattern of the studied COMT SNPs was analyzed in Haploview. D' and r2: measures of linkage disequilibrium between two genetic markers. LOD the logarithm of the odds for LD