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Table 1 Linage disequilibrium (LD) of the combined studied SNPs in PD patients and healthy controls

From: Roles of functional catechol-O-methyltransferase genotypes in Chinese patients with Parkinson’s disease

  Control group PD group
rs4633 rs4818 rs4680 rs4633 rs4818 rs4680
rs6269 D’ 0.90 0.94 0.77 0.91 0.98 1.00
LOD 8.05 48.14 4.84 4.43 48.84 5.49
r 2 0.18 0.85 0.12 0.14 0.92 0.16
rs4633 D’ - 1.00 0.95 - 0.91 1.00
LOD - 10.20 41.80 - 3.85 49.53
r 2 - 0.21 0.83 - 0.13 0.96
rs4818 D’ - - 0.94 - - 1.00
LOD - - 7.47 - - 4.88
r 2 - - 0.17 - - 0.16
  1. The LD pattern of the studied COMT SNPs was analyzed in Haploview. D' and r2: measures of linkage disequilibrium between two genetic markers. LOD the logarithm of the odds for LD