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Table 6 Kinetics of the enzyme activity in full-length GAC, KGA, and the dual N- and C-terminal deletion mutant

From: Serial deletion reveals structural basis and stability for the core enzyme activity of human glutaminase 1 isoforms: relevance to excitotoxic neurodegeneration

Protein

Km (mM)

Vmax (μmol/min per ml)

GAC FL

25.43 ± 3.82

40.01 ± 2.74

KGA FL

22.99 ± 3.15

38.04 ± 2.29

GLS1 219–550 AA

29.04 ± 2.9

48.77 ± 2.35