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Table 6 Kinetics of the enzyme activity in full-length GAC, KGA, and the dual N- and C-terminal deletion mutant

From: Serial deletion reveals structural basis and stability for the core enzyme activity of human glutaminase 1 isoforms: relevance to excitotoxic neurodegeneration

Protein Km (mM) Vmax (μmol/min per ml)
GAC FL 25.43 ± 3.82 40.01 ± 2.74
KGA FL 22.99 ± 3.15 38.04 ± 2.29
GLS1 219–550 AA 29.04 ± 2.9 48.77 ± 2.35