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Fig. 1 | Translational Neurodegeneration

Fig. 1

From: Opioid system in L-DOPA-induced dyskinesia

Fig. 1

Endogenous opioid peptide and receptor gene expression and alteration in basal ganglia under PD and LID conditions. A sketch of basal ganglia local circuit map shows characteristic expression patterns of endogenous opioid peptide and receptor genes in different sub-regions. The inset highlights signature alterations of opioid peptide and receptor expression in the dorsal striatum under PD and LID conditions. Oprm1: μ opioid receptor; Oprd1: δ opioid receptor; Oprk1: κ opioid receptor; Penk: preproenkephalin; Pdyn: pre-prodynorphin; GPe: globus pallidus external segment; STh: subthalamic nucleus; SNc: substantia nigra pars compacta; SNr: substantia nigra pars reticulata

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Translational Neurodegeneration

ISSN: 2047-9158

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