Fig. 4

Salidroside inhibits tau-induced neurotoxicity by activating the GSK-3β in vivo. a Tau-expressing transgenic flies were treated with Sal or Donepezil for 30 days. The levels of total GSK-3β, total tau, phosphorylated GSK-3β and phosphorylated tau were detected and compared with the control group. b The expression levels of GSK-3β, tau and their phosphorylated form were detected. All data are presented as mean ± SEM.*p < 0.05, **p < 0.01 (one-way ANOVA and Tukey’s test)