Table 1 Clinical Characteristics of patients with Benign Tremulous Parkinsonism
From: Benign tremulous Parkinsonism: a unique entity or another facet of Parkinson’s disease?
Study | Sex (M/F) | Mean Age of onset (range) | Initial symptoms | Disease duration (years, range) | Treatment response | Family history |
|---|---|---|---|---|---|---|
Josephs et al. | 10/6 | 58.5 (42–71) | Unilateral hand rest tremor (13/16) | 11.1 (8–25) | No benefit by LDa(≥600 mg/d) | 10/16 |
Selikhova et al. | 9/7 | 59 (30–72) | Unilateral hand rest tremor (11/16), rest and postural/action tremor (5/16) | 24 (12–50) | Not responsive to LD (9/15), though 6/15 had early benefit | 5/15 |
Leventoglu et al. | 16/7 | 66.6 (50–89) | Unilateral hand rest tremor (18/23) | 5 | Little improvement to LD (11/18) | 4/23 |