Fig. 2
Deregulated miRNAs in CSF of patients with Alzheimer’s disease (n = 10) compared to patients with other types of dementia (n = 10). Aligned scatter plots show relative expression levels (REL) of let-7i-5p a, miR-15a-5p b, and miR-29c-3p c. Black bars indicate median values. In part d the ratio RELmiR-29c-3p/RELmiR-15a-5p is calculated for each patient and plotted in an aligned scatter plot. The red dotted line indicates a cutoff value of 0.92 where AD patients can be separated from control patients with a sensitivity of 90 % and a specificity of 100 %