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Fig 2 | Translational Neurodegeneration

Fig 2

From: Methylation status of DJ-1 in leukocyte DNA of Parkinson’s disease patients

Fig 2

Bisulfite specific PCR-based sequencing analysis of two CpG islands methylation in 40 PD patients and 40 normal controls. a and b Unmethylated cytosines (c) were converted to uracil (U) after bisulfite treatment and amplified as thymines (T) in PCR amplication. Unmethylated CpG sites 1–5 in CpG1 island and CpG sites 9–16 in CpG2 island were shown here as an example. c and d All the CpG sites of these two CpG islands were unmethylated. Here are the methylation of CpG1 island and CpG2 island from 5 PD and 5 NC cases, and the rest cases showed the exact same methylation pattern

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