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Table 4 Comparison between previous studies and present study

From: A survey of impulse control disorders in Parkinson’s disease patients in Shanghai area and literature review

Study population

Sample Size

Screen instruments

Frequency of compulsive behaviors

Risk factors

Dosage of drugs

(ICD vs non ICD mg/d, mean)

Reference

Taiwan

268

DSM-IV-TR criteria for

PG and BE,

McElroy’s criteria for CS

Voon’s criteria (2006) for HS

ICD 4.48 %

PG 1.49 %, HS 2.99 %

CS 0 %, BE 0.37 %

Dopamine agonist

TLED

Male gender

TLED (ICD group): 741.94 DA-LED (ICD group): 105

4

Brazil

152

QUIP

QUIP results:

ICD 18.4 %

PG 1.3 %, HS 11.8 %

CS 10.5 %, BE 7.9 %

Smoking

Use of pramipexole

TLED: 732.8 vs 644.4

Pramipexole: 2.9 vs 0.85

(equivalent to 290 vs 85)

5

North America

3090

Massachusetts Gambling Screen

MIDI

DSM-IV-TR

ICD 13.6 %

PG 5 %, HS 3.5 %

CS 5.7 %, BE 4.3 %

DA

combination of DA & Levodopa

younger age, male sex

current smoking

being unmarried

living in the United States

family history of gambling

DA-LED: 200 ~ 450 vs 150 ~ 400

(listed as interquartile in patients taking DA)

Levodopa: 621 vs 461 (in patients taking levodopa only)

6

Finland

575

SOGS

QUIP

QUIP results:

ICD 34.8 %

PG 8.8 %, HS 22.8 %

CS 10.1 %, BE 11.8 %

Depression, Male sex

Younger age

Age of disease onset

Current alcohol use

NA

7

Italy

805

QUIP for screen

Other criteria for confirmation

ICD 8.1 %

PG 3.2 %, HS 3.0 %

CS 1.0 %, BE 2.4 %

dopamine agonist

Male sex, levodopa

younger age, Amantadine

NA

8

Japan

118

QUIP for screen

Other criteria for confirmation

QUIP results vs Actual prevalence

ICD 28 % vs 12.9 %

PG 14 % vs 6.5 %

HS 14 % vs 3.2 %

CS 10.8 % vs 3.2 %

BE 10.8 % vs 3.2 %

younger age

longer disease duration

TLEDD, Levodopa

Earlier age of onset

ICB vs non-ICB

Levodopa: 676 vs 520

DA-LED: 139 vs 71.6

9

China

312

SOGS, DSM-IV

Lejoyeux’s Compulsive Shopping questionnaire;

specially designed hypersexuality questionnaire;

ICD 3.53 %

PG 0.32 %, HS 1.92 %

CS 0.32 %, BE 0.32 %

Dopamine agonist

Alcohol use

Levodopa: 345.5 vs 357.01

DA-LED: 142.37 vs 35.45

10

South Korea

1167

MIDI

ICD 5.9 %

PG 1.3 %, HS 2.8 %

CS 2.5 %, BE 3.4 %

Dopamine agonist

Levodopa

Levodopa: 656 vs 544

DA-LED: 145 vs 99

11

Malaysian

200

QUIP

QUIP results based on patient report

ICD 15.4 %

PG 2.6 %, HS 8.2 %

CS 3.6 %, BE 8.7 %

Male gender

Longer PD duration

PD patients:

TLED: 527.7

DA-LED: 73.7

12

Present study

217

MIDI

Voon’s criteria (2007) for each ICD

ICD 4.15 %

PG 1.38 %, HS 1.84 %

CS 0.46 %, BE 0.46 %

None

Levodopa: 791.67 vs 425.0

DA-LED: 119.4 vs 60.5

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  1. SOGS: modified South Oaks Gambling Screen. QUIP: Questionnaire for Impulsive Compulsive Disorders in Parkinson’s Disease
  2. MIDI: Minnesota Impulsive Disorders Interview. ICB: impulsive compulsive behavior
  3. DA-LED: Dopamine agonist levodopa equivalent dosage. TLED: Total levodopa equivalent dosage