Skip to main content
Fig. 4 | Translational Neurodegeneration

Fig. 4

From: No apparent transmission of transgenic α–synuclein into nigrostriatal dopaminergic neurons in multiple mouse models

Fig. 4

Overexpression of hα-syn in tetO-SNCA single and Pitx3–tTA::tetO–SNCA bigenic mice. a Western blots show expression of hα-syn and m/hα-syn in the cerebellum of 1–month–old tetO-SNCA single and Pitx3–tTA::tetO–SNCA bigenic mice. α-tubulin was used as loading control. Bar graphs depict the signal intensity. Data were presented as mean ± SEM. b Western blot shows expression of hα-syn and m/hα-syn in the whole brain of 18–month–old Pitx3–tTA, tetO-SNCA single, Drd1a–rtTA::tetO–SNCA bigenic and Pitx3–tTA::tetO–SNCA bigenic mice. β-actin was used as loading control. c Western blots show expression of hα-syn and m/hα-syn in the striatum of 1–month–old tetO-SNCA single and Pitx3–tTA::tetO–SNCA bigenic mice. α-tubulin was used as loading control. Bar graphs depict the signal intensity. Data were presented as mean ± SEM

Back to article page