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Table 2 Candidate physiological biomarkers for ALS

From: New developments and future opportunities in biomarkers for amyotrophic lateral sclerosis

 

Evaluated biomarkers

Measures of LMN loss

Motor unit number estimation (MUNE)

 

Axonal excitability

 

Electrical impedance myography (EIM)

 

Muscle ultrasound (MUS)

Measures of UMN loss

Transcranial magnetic stimulation (TMS)