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Table 1 Summary of the clinical trials using fetal brain cells for treatment of PD

From: Development of stem cell-based therapy for Parkinson’s disease

No. of patients with cell transplantation

Follow-up Time

Symptom improvement

PET DA neuron survival

Side effect of Dyskinesia

Pathological lewy body

References And publication year

1

12 months

1/1

Yes

No

Not available

[43]

6

10–72 months

4/6

Yes

No

Not available

[77]

5

18–24 months

2/5

Yes

No

Not available

[36]

20/40

3 years

17/20

Yes

No

Not available

[45]

23/34

24 months

6/23

Yes

56 % dyskinesia

Not available

[48]

2

8 years

2/2

Yes

50 % dyskinesia

Not available

[7]

5

9–14 years

Not available

Yes

Not available

Not available

[42]

1

14 years

1/1

Yes

Dyskinesia

Lewy body

[55]

2

11–16 years

Not available

Yes

Not available

Lewy body

[54]

33

2–4 years

45 %

Yes

Not available

Not available

[8]

3

13–16 years

Yes

Yes

Not available

Not available

[8]

2

18 and 15 years

2/2

Yes

Not available

Not available

[24]

  1. Note: 20/40 and 23/34 indicates that 20 of 40 patients and 23 of 34 patients are in the cell transplantation group and the other patients are in the control group