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Table 1 Summary of the clinical trials using fetal brain cells for treatment of PD

From: Development of stem cell-based therapy for Parkinson’s disease

No. of patients with cell transplantation Follow-up Time Symptom improvement PET DA neuron survival Side effect of Dyskinesia Pathological lewy body References And publication year
1 12 months 1/1 Yes No Not available [43]
6 10–72 months 4/6 Yes No Not available [77]
5 18–24 months 2/5 Yes No Not available [36]
20/40 3 years 17/20 Yes No Not available [45]
23/34 24 months 6/23 Yes 56 % dyskinesia Not available [48]
2 8 years 2/2 Yes 50 % dyskinesia Not available [7]
5 9–14 years Not available Yes Not available Not available [42]
1 14 years 1/1 Yes Dyskinesia Lewy body [55]
2 11–16 years Not available Yes Not available Lewy body [54]
33 2–4 years 45 % Yes Not available Not available [8]
3 13–16 years Yes Yes Not available Not available [8]
2 18 and 15 years 2/2 Yes Not available Not available [24]
  1. Note: 20/40 and 23/34 indicates that 20 of 40 patients and 23 of 34 patients are in the cell transplantation group and the other patients are in the control group