Table 1 Sensitivity analyses of the prevalence of selected non-motor symptoms of PD after diagnosis
From: Meta-analyses on prevalence of selected Parkinson’s nonmotor symptoms before and after diagnosis
PD cases | Controls | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
All data | Sample size ≥50 | Studies with controls | Not self-reported single symptom | All data | Sample size ≥50 | Not self-reported single symptom | ||||||||
N | % | N | % | N | % | N | % | N | % | N | % | N | % | |
Anxiety | 54 | 39.9 ± 2.3 | 46 | 39.7 ± 2.5 | 5 | 33.9 ± 12.6 | 33 | 36.3 ± 2.4 | 5 | 19.1 ± 7.2 | 4 | 16.7 ± 7.7 | 2 | 17.3 ± 11.8 |
Constipation | 50 | 50 ± 2.3 | 34 | 47.4 ± 2.5 | 14 | 44.8 ± 4.6 | 11 | 58.9 ± 5.8 | 14 | 17.7 ± 3.5 | 9 | 21 ± 4.2 | 3 | 16.7 ± 4.1 |
Depression | 170 | 36.6 ± 1.4 | 136 | 35.7 ± 1.6 | 25 | 36.3 ± 3.7 | 145 | 35.6 ± 1.5 | 25 | 14.9 ± 1.8 | 20 | 15 ± 1.9 | 20 | 13.7 ± 1.8 |
EDS | 74 | 33.9 ± 1.7 | 58 | 32.9 ± 1.9 | 22 | 32.8 ± 2.3 | 46 | 35.4 ± 1.8 | 22 | 10.5 ± 1.6 | 14 | 11.6 ± 2.1 | 17 | 9.2 ± 1.3 |
Hyposmia | 39 | 75.5 ± 4.2 | 21 | 71 ± 5.9 | 17 | 76.5 ± 3.7 | 36 | 78.1 ± 2.7 | 17 | 19.1 ± 3.1 | 5 | 19.8 ± 5.5 | 16 | 20.1 ± 3.3 |
RBD | 71 | 37 ± 1.8 | 51 | 36 ± 2 | 7 | 34.6 ± 8 | 53 | 39 ± 2.2 | 6 | 7 ± 2.4 | 3 | 7.4 ± 3.3 | 5 | 6.8 ± 3.4 |