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Table 4 Comparison of R 2 differences of relationships between baseline and 12-month scores in cognitive measures

From: Comparison of cognitive and UHDRS measures in monitoring disease progression in Huntington’s disease: a 12-month longitudinal study

  Differences in R2values [95% CI]
UHDRS cognitive component MMSE - WORLD MMSE - Sevens MoCA
Global cognitive z-score -0.0 [-0.1 – 0.1] 0.2 [0.0 – 0.4]* 0.2 [0.0 – 0.5]* 0.1 [-0.0 – 0.3]
UHDRS cognitive component - 0.2 [0.0 – 0.5]* 0.2 [0.0 – 0.4]* -0.1 [-0.0 – 0.4]
MMSE - WORLD - - 0.0 [-0.2 – 0.1] -0.1 [-0.3 – 0.1]
MMSE - Sevens - - - -0.1 [-0.3 – 0.2]
  1. *The estimated 95% CI of R2 differences is greater than ‘0.0’ which suggests that the difference in R2 values between the two cognitive measures tested could be considered significant.