Parameter | Time | |
---|---|---|
1st week | 24th week | |
BEHAVE-AD | ||
Paranoid and delusion ideation | 3.05 ± 0.38 | 3.26 ± 0.36 |
Hallucinations | 3.82 ± 0.52 | 3.95 ± 0.61 |
Activity disturbances | 6.55 ± 0.68 | 7.34 ± 0.71* |
Aggressiveness | 5.06 ± 0.30 | 5.12 ± 0.29 |
Diurnal rhythm disturbances | 2.81 ± 0.33 | 3.45 ± 0.42* |
Affective disturbances | 3.05 ± 0.43 | 3.28 ± 0.35 |
Anxieties and phobias | 2.27 ± 0.35 | 3.19 ± 0.38* |
NPI Mean score | ||
Delusions | 1.55 ± 0.69 | 1.83 ± 0.56 |
Hallucinations | 1.30 ± 0.51 | 1.58 ± 0.47 |
Agitation | 5.55 ± 0.90 | 7.48 ± 0.88* |
Depression | 4.21 ± 0.81 | 4.29 ± 0.36 |
Anxiety | 2.32 ± 0.81 | 2.44 ± 0.91 |
Euphoria | 3.75 ± 0.65 | 3.82 ± 0.76 |
Apathy | 3.33 ± 0.71 | 3.09 ± 0.80 |
Disinhibition | 2.75 ± 0.68 | 2.91 ± 0.77 |
Ignitability | 3.25 ± 0.92 | 5.17 ± 0.83* |
Aberrant motor behavior | 4.25 ± 0.69 | 4.38 ± 0.66 |
Sleep disturbance | 5.32 ± 0.83 | 6.05 ± 0.69* |
Appetite | 4.08 ± 0.57 | 4.38 ± 0.61 |
DFA of actigraph activity | ||
Diurnal activity | 0.82 ± 0.17 | 0.86 ± 0.14 |
Evening activity | 0.87 ± 0.13 | 0.90 ± 0.11 |
Nocturnal activity | 0.93 ± 0.16 | 1.03 ± 0.16* |