Figure 4
Effect of 17-AAG on NFT area in JNPL3 mice. Area of AT8 immunopositivity in the medulla of JNPL3 mice treated with 17-AAG. Boxes represent 25th and 75th percentiles; medians are the lines across the boxes; whisker caps represent 5th and 95th percentiles; and open circles are outliers. Doses of 17-AAG are shown as 0 mg/kg, 5 mg/kg, or 25 mg/kg. Top: Males. Bottom: Females.