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Table 1 Effect of As on the activities of Na + K + ATPase, Mg 2+ ATPase, Ca 2+ ATPase in the striatal and midbrain tissue of control and experimental mice

From: Asiaticoside, a trisaccaride triterpene induces biochemical and molecular variations in brain of mice with parkinsonism

  Striatal tissue Midbrain
Particulars Group I
(Control)
Group II
(MPTP induced)
Group III
(MPTP induced + AS Treated)
Group IV
(AS Control)
Group I
(Control)
Group II
(MPTP induced)
Group III
(MPTP induced + AS Treated)
Group IV
(AS Control)
Na+ K + ATPase 0.33 ± 0.01 0.25 ± 0.03a* 0.33 ± 0.04b* 0.34 ± 0.06NS 0.34 ± 0.13 0.23 ± 0.03a* 0.34 ± 0.02b* 0.34 ± 0.02NS
Mg2+ ATPase 0.44 ± 0.03 0.32 ± 0.02a* 0.35 ± 0.03b* 0.44 ± 0.04NS 0.44 ± 0.03 0.35 ± 0.06a* 0.43 ± 0.02b* 0.45 ± 0.02NS
Ca2+ ATPase 0.54 ± 0.06 0.34 ± 0.04a* 0.35 ± 0.03b* 0.44 ± 0.08NS 0.54 ± 0.08 0.33 ± 0.01a* 0.46 ± 0.01b* 0.56 ± 0.02NS
  1. Na+ K +, Mg2+, Ca2+ ATPase = μmoles of Pi liberated/min/mg protein. Each value expressed as mean ± S.D for six mice (n = 6) in each group. Statistically significance at *p < 0.05; a group I vs group II, b group II vs group III and (NS) non-significant group IV vs group I.