Table 1 Randomized controlled trial comparing DBS to optimal medical management
Author, year | Number of patients | Follow up | Target | Results (primary outcome) |
|---|---|---|---|---|
Deuschl et al., 2006 [53] | 156 | 6 months | BL STN | -Quality of life better with DBS |
-Motor symptoms better with DBS. | ||||
Weaver et al., 2009 [54] | 255 | 6 months | BL STN or GPi | Dyskinesia- free ON time 4.6 hours longer with DBS |
Williams et al., 2010 [55] | 366 | 12 months | BL STN or GPi | -Quality of life better with DBS |