Figure 4From: Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblastsEffects of α-syn on mitochondrial function in human primary cortical neurons, astrocytes and skin-derived fibroblasts. The BCR and UCR were determined in (i) human primary cortical neurons, (ii) astrocytes and (iii) skin-derived fibroblasts pre-treated with 5 μM recombinant α-syn for 24 hours. Significance *p < 0.05 compared to non-treated cells. (n = 4 for each treatment group).Back to article page