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Figure 1 | Translational Neurodegeneration

Figure 1

From: Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts

Figure 1

α-syn uptake in human primary cortical neurons cells. (i) Confocal microscopy analysis of α-syn uptake after 30 and 60 min in human cortical neurons. Staining for Alexa-Fluor-488-labelled α-syn in human neurons: Top, double staining for MAP-2/red and DAPI/blue; Centre, double staining for α-syn/green and DAPI/blue; Bottom, Merged MAP-2/red, α-syn/green and DAPI/blue. (ii) The histogram represents the semi-quantification of the immunostaining intensity. Intensity has been quantified using ImageJ 10.2. This experiment has been performed in triplicate with primary cultures of cortical neurons prepared from three different brain samples. Three individual microscopic fields were analysed for each treatment and the SEM for the data was determined to be 5%. * indicate the level of significance (p < 0.05).

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Translational Neurodegeneration

ISSN: 2047-9158

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