Figure 6
From: Erythropoietin prevents PC12 cells from beta-amyloid-induced apoptosis via PI3K⁄Akt pathway
Involvement of PI3K/Akt in the effects of Epo on Abeta (25-35) -induced cell apoptosis determined by Hoechst33258 staining. As shown in the following graph, We treated the cells with PI3K inhibitor LY294002 and found the protective effects of Epo on the Abeta(25-35)-induced cell apoptosis were diminished (P < 0.05). Three independent experiments were performed in duplicate (*: P < 0.05 vs. the controls and #: P < 0.05 vs. 20 μM Abeta(25-35))