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Figure 1 | Translational Neurodegeneration

Figure 1

From: Mitochondrial neuronal uncoupling proteins: a target for potential disease-modification in Parkinson's disease

Figure 1

Simplified diagram of oxidative phosphorylation and involvement of uncoupling proteins (UCPs) in mitochondrial uncoupling. UCPs act as an alternative route to dissipate proton gradient across the inner membrane and bypass ATP synthase. Through mitochondrial uncoupling, UCPs help to minimize ROS generation caused by interactions between leaking electrons (e-) and molecular oxygen (O2).

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Translational Neurodegeneration

ISSN: 2047-9158

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