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Figure 5 | Translational Neurodegeneration

Figure 5

From: Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system

Figure 5

42 immunoreactivity (greyscale) of neonatal rat cortical neurons (A, C) cultured (under normal conditions (control) or (B, D) exposed to 20 nM exocytosis inhibitor tetanus toxin (TeNT) for 24 h. (A and B) phase contrast images, (B and D) fluorescence images of corresponding cells. Both drugs induce intracellular accumulation of Aβ42. Bar, 50 nM. Intraneuronal Aβ42 is increased and accumulated in the neurites.

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