Figure 2
From: Intracellular distribution of amyloid beta peptide and its relationship to the lysosomal system
Double immunostaining for Aβ 42 (green fluorescence) and different subcellular markers (red fluorescence) in RA differenatiated SH-SY5Y cells. (A) Rab8 (Golgi derived vesicles marker), (B) Rab9 (trans-Golgi network, Golgi-derived vesicles and late endosome marker), (C) LAMP-2 (late endosome and lysosome marker), (D) Rab5 (early endosome marker), (E) Rab3 (exocytotic vesicle marker) and (F) VAMP2 (synaptobrevin, marker for synaptic vesicles) were used as subcellular organelle markers. Scale bar, 5 μm.