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Table 2 Asymptomatic persons with positive biomarkers of AD [modified from 10]

From: Prevention strategies for Alzheimer’s disease

Stage Biomarkers or evidence
  Aß (amyloid PET or CSF) Neuronal injury (tau in CSF, FDG-PET, structural MRI) Evidence of cognitive decline
asymptomatic cerebral amyloidosis (ACA) positive negative negative
ACA + neuronal injury (NI) positive positive negative
ACA + NI + subtle cognitive decline positive positive positive