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Table 2 Current available, approved dopamine agonists

From: Drug therapy in patients with Parkinson’s disease

compound dose range administration half life
bromocriptine 10 - 50 oral, t.i.d. 3 – 6
lisurid 0.2 - 3 oral, 12 i.d. 2
pergolid 0.5 - 6 oral, t.i.d. 6-8
dihydro-α-ergocryptine 20 - 120 oral, t.i.d. 16
cabergoline 0.5 - 4 oral, o.i.d. 63
rotigotine 2 - 16 patch, t.i.d. 24
Pramipexol [retarded release] 0.25 - 4.5 oral, t.i.d.[o.i.d. – b.i.d.] 8 [24]
Ropinirol [retarded release] 4 - 24 oral, o.i.d. [o.i.d. – b.i.d.] 6 [24]
Piribedil retarded release 50 - 250 oral, t.i.d. 21
  1. Dose range is given in mg, only approved dopamine agonist with oral or transdermal administration are listed, plasma half life is given in hours, 10 mg bromocriptine correspond to approximately 400 mg LD/DDI.