Table 3 Demographics of the study population in ADNI
CN (n = 109) | sMCI (n = 117) | pMCI (n = 66) | AD (n = 90) | |
|---|---|---|---|---|
Age, mean (SD), years | 75.63 (5.22) | 74.34 (7.60) | 74.21 (7.58) | 74.89 (7.72) |
Female, n (%) | 54 (49.54) | 37 (31.62) | 25 (36.76) | 39 (44.32) |
APOE ε4 genotype carriers, n (%) | 26 (23.85) | 55 (47.00) | 42 (61.76) | 63 (69.23) |
CSF α-synuclein, mean (SD), ng/L | 0.46 (0.17) | 0.54 (0.22) | 0.56 (0.20) | 0.61 (0.24) |
MMSE score, mean (SD) | 29.07 (1.05) | 27.15 (1.64) | 26.58 (1.77) | 23.39 (1.80) |
CSF Aβ42, mean (SD), ng/L | 208.70 (52.36) | 174.69 (55.28) | 148.75 (41.52) | 143.99 (38.31) |
CSF t-tau, mean (SD), ng/L | 69.08 (29.85) | 97.31 (64.77) | 112.00 (41.52) | 122.83 (57.09) |
CSF p-tau, mean (SD), ng/L | 25.04 (13.93) | 32.76 (18.31) | 39.50 (17.18) | 41.48 (19.73) |
Hippocampus volume, mm3 | 6648.16 (766.59) | 5964.07 (986.76) | 5522.46 (1044.15) | 5217.39 (1043.40) |