Fig. 2
![Fig. 2](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs40035-020-00203-4/MediaObjects/40035_2020_203_Fig2_HTML.png)
SOD1 mutation (G93A) induces apoptosis. a Western blot analysis verified the protein levels of Hif1α, Mef2c, Mctp1, Rarb, Bax, and Bcl2 in three different NSC-34 cell lines. b Quantification analysis of western blot. The data represent the average ± SEM of 3 separate experiments. Significantly different at *, p < 0.5; **, p < 0.05. c Hif1α and Mef2c transcripts were increased in mtNSC-34 cells. d Mctp1 and Rarb transcripts were decreased in mtNSC-34 cells e miR-18b (miR-18b-5p) was reduced in mtNSC-34 cells. f LDH releases analysis explained that SOD1 mutation (G93A) induces apoptosis. g Bax mRNAs were upregulated and Bcl2 mRNAs were downregulated in mtNSC-34 cells. Significantly different at *, p < 0.05; **, p < 0.005. The experiments were replicated 3 times