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Table 2 Serial epidemiological studies of PD patients with WO and dyskinesia in Asian and Caucasians

From: Prevalence of wearing-off and dyskinesia among the patients with Parkinson’s disease on levodopa therapy: a multi-center registry survey in mainland China

Countries

PD sample

Design

WO prevalence (%)

Dyskinesia prevalence (%)

References

UK

87

Community based

40.0(MF)

28

Schrag A, et al. Brain, 2000[2]

China

63

Hospital based, single center

44.4

17.5

Liu CF, et al. Chin J Neurol, 2003[5]

USA & Europe

289

Hospital based, multi-center

43.9*(MF)

-

Stacy M, et al. Mov Disord, 2005[19]

Turkey

555

Hospital based, single center

46.3

30.1

Benbir G, et al. Clin Neurol Neurosurg, 2006[11]

Chile

124

Hospital based, single center

52.0

47.2

Juri-Claveria C, et al. Rev Neurol, 2007[21]

Hong Kong

98

Hospital based, single center

74.5(MF)

77.6

Kum WF, et al. J Clin Neurosci, 2009[4]

Czech Republic

563

Hospital based, multi-center

66.7

-

Bares M, et al. J Neural Transm, 2012[18]

Japan

1453

Hospital based, single center

44.7

-

Yoritaka A, et al. Parkinsonism Relat Disord, 2013[22]

Italy

617

Hospital based, multi-center

56.9

-

Stocchi F, et al. Parkinsonism Relat Disord, 2014[20]

China

1558

Hospital based, multi-center

46.5

10.3

Present study

  1. *WO diagnosis according to UPDRS-IV, MF Motor fluctuation.