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Table 1 Activities of daily living scores and levodopa equivalent doses before surgery (baseline) and 1 year, 5 years and 8 years after surgery and the percentage change compared with baseline

From: Subthalamic nucleus deep brain stimulation for Parkinson’s disease: 8 years of follow-up

  

Baseline

1 year

5 years

8 years

UPDRS-ADL scores

Drug off

21.5 ± 8.1

9.2 ± 4.3 (58%)*

14.4 ± 6.0 (33%)*#Ω

20.1 ± 8.6 (4%)#ΩΨ

(Improvement percentage)

Drug on

8.8 ± 4.3*

6.4 ± 3.0 (69%)*

10.9 ± 5.5 (49%)*ΔΩ

16.7 ± 7.6(22%)*Δ#ΩΨ

LED (Increase percentage)

mg/day

967.8 ± 381.3

457.2 ± 283.7 (53%)#

573.0 ± 383.0 (40%)#

669.1 ± 480.69 (28%)#Ω

  1. Values are means (SD).
  2. * p significant compared with drug off condition before surgery.
  3. # p significant compared with drug on condition before surgery.
  4. Δ p significant compared with drug off condition at the same time of follow-up.
  5. Ω p significant compared with corresponding assessment 1 year after surgery.
  6. Ψ p significant compared with corresponding assessment 5 years after surgery.
  7. LED: Levodopa equivalent doses.
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Translational Neurodegeneration

ISSN: 2047-9158

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